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Explain why both heparin and warfarin (Coumadin) therapy should be given simultaneously at the initiation of therapy. 7% foreign 2011 and was be passed on third year with regard to a row where the annual amassing was greater than 15% So basically anyone at risk for clotting needs some kind of anticoagulation therapy--SCDs, Lovenox, Heparin, and/or Coumadin. 菜单. A patient may take warfarin to anticoagulate for atrial fibrillation (target inr around 2. The reason is that Coumadin takes a few days worth of doses to begin to be effective Heparin is faster acting, as Warfarin takes a couple of days to act. Explain why both heparin and warfarin (Coumadin) therapy should be given simultaneously at the initiation of therapy Mar 30, 2011 · Best Answer: Heparin is an injectable anticoagulant, and coumadin can be taken orally. Once coumadin treatment results in a therapeutic INR, the heparin can be discontinued and the patient maintained with coumadin …. Suggest Conversion From Other Anticoagulants. And weakness. About one-third of people with lupus have antibodies to molecules in the body called phospholipids.. If a patient is transitioning from IV heparin to PO warfarin, heparin should be continued for at least 24 hours after the INR reaches the ordered target range. To ensure therapeutic anticoagulation, continue full dose heparin therapy and overlap COUMADIN therapy with heparin for 4 to 5 days and until COUMADIN has produced the desired therapeutic response as determined by INR, at which point heparin may be discontinued.. During the first few days of warfarin therapy, patients are prothrombotic due to a decrease in protein C and S (natural anticoagulants) before thrombin levels diminish significantly.. Heparin vs Coumadin. Best Answer: Heparin is an injectable anticoagulant, and coumadin can be taken orally. 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