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Symbyax (olanzapine and fluoxetine hydrochloride) is a combination of a thienobenzodiazepine, a type of atypical antipsychotic, and a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI) used to treat …. Clozapine (FazaClo), olanzapine (Zyprexa), quetiapine (Seroquel) and risperidone (Risperdal), which treat schizophrenia, bipolar disorder or other mental illnesses, have all been linked to increased risk of weight gain How Zyprexa Alters Your Metabolism. 1. I'm still keeping an eye on things but I think I may have gained just a bit. I eat no different than before i was on zyprexa. I had to go on a weight loss prescription pill to lose it. I am walking 4 miles about 4 times a week. Jun 08, 2005 · I posted on the old board about not any weight on Zyprexa but I think I have gained a bit after all. Sep 16, 2014 · Weight loss on antipsychotics is possible: study. My weight has leveled off for several years. 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